Optimal daily intake 1 ppm or 1 mg/day.

Based on drinking a liter(L) or quart of water/day.
· 1 mg/L = 1 mg/1,000 ml
· 1 ml water = 1 gm or 1,000 mg
· therefore 1 mg/1,000 gm (water) or 1 mg/1,000,000 mg (1 ppm)
· ppm = mg/L or mg/kg (water)
 

% solutions and conversion of ppm to % solutions.
· gm solute/100 ml solvent.
· 10% solution = 10 gm/100 ml
0.4% = 0.4 gm or 400 mg/100 ml
· 100 ppm = 100 mg/L = 0.1 gm/L = .01 gm/100 ml = 0.01%
· 1000 ppm = 1000 mg/L = 1 gm/L = 0.1 gm/100 ml = 0.1%

Simple conversion of fluoride ppm to % solution---___ppm X 0.0001= ___% fluoride in solution.

Simple conversion of % fluoride in solution to ppm--___% fluoride X 10,000=____ppm

Fluoride Content of Toothpastes:
-0.221% NaF(45% F) = 0.1%F = 1000 ppm = 1 mg/gm of toothpaste.
-0.41% SnF2(24% F) = 0.1%F = 1000 ppm =1 mg/gm of toothpaste.
Sn = 120, F=l9 X 2 = 38, total MW =158-- 38/158= 0.25X 0.4 = 0.1%F
-0.76% MFP (14% F) = 0.1%F = 1000 ppm =1mg/gm of toothpaste.
 

Fluoride Content of Gels and Liquids:
-1.23% F (APF) = 12,300 ppm =12.3 gm/L =12.3mg F/ml.
Large fluoride tray may hold 5 ml or 61 mg F total.
-0.05% NaF = 0.023%F = 230 ppm = 230 mg/L= 0.23 mg/ ml.
Na= 23mw, F= 19 mw total=42 , 19/42= 0.45 X 0.05=0.023
 

Lethal Dosage:
Adult = 1.25 gms F or 2.5 gms of NaF is lethal. (8-16 mg/kg of body weight). Best to consider 8 mg of F/kg body weight as lethal adult dose.
e.g. 80Kg adult x 8mg/Kg =640 mg of F.
For a child 5 mg of F/kg body weight considered toxic.
e.g. 20 Kg child X 5 mg/Kg body weight= 100 mg of F toxic.
Small Fluoride tray may hold 2 ml each. APF = 12.3 mg F/ml,
2 trays = 4 ml x 12.3 mg= about 50 mg. This is half the toxic dose.